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What is 5-MeO-MiPT?

5-Methoxy-N-methyl-N-isopropyltryptamine (also known as 5-MeO-MiPT and Moxy) is a psychedelic substance of the tryptamine class. It has become increasingly popular in recent years for its tactile effects that serve to enhance libido and sexual pleasure.

5-MeO-MiPT is chemically related to tryptamines like 5-MeO-DMT and 5-MeO-DiPT. It produces its psychoactive effects through activity at serotonin receptors in the brain.

The synthesis and pharmacology of 5-MeO-MiPT was first reported in 1985 by David Repke and Alexander Shulgin. Its effects in humans was documented in Shulgin’s book TiHKAL (“Tryptamines I Have Known and Loved”).

Chemical Properties of 5-MeO-MiPT

5-MeO-MiPT is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 5-MeO-MiPT is substituted at R5 of its indole heterocycle with a methoxy (MeO) functional group CH3O−; it also contains a methyl group and an isopropyl chain bound to the terminal amine RN of its tryptamine backbone (MiPT).

What are the Effects of 5-MeO-MiPT?

5-MeO-MiPT’s psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a [[Agonist#Agonists|partial agonist] and additional mechanisms of action such as the inhibition of MAO (i.e. digestive enzymes in the stomach) have also been speculated upon, though this has yet to be demonstrated scientifically.

Some of the most commonly reported effects of 5-MeO-MiPT are:

• Stimulation
• Increased libido
• Heightened tactile sensations
• Colour enhancement
• Pattern recognition enhancement
• Depersonalization
• Spontaneous bodily sensations

Some potential Side Effects of 5-MeO-MiPT:

• Nausea
• Vasoconstriction
• Increased heart rate
• Abnormal heartbeat
• Headaches
• Dehydration
• Bodily pressures

Legality

Where is 5-MeO-MiPT Illegal?

• Brazil
• Germany
• Japan
• United Kingdom
• Latvia
• Switzerland